Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
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چکیده
منابع مشابه
Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
The HMGA1 and HMGA2 genes code for proteins belonging to the High Mobility Group A family. Several genes are negatively or positively regulated by both these proteins, but a number of genes are specifically regulated by only one of them. Indeed, knock-out of the Hmga1 and Hmga2 genes leads to different phenotypes: cardiac hypertrophy and type 2 diabetes in the former case, and a large reduction...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2014
ISSN: 2046-6390
DOI: 10.1242/bio.20146759